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Anti-Human TEX14 Polyclonal Antibody (PTX20167)

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概述
货号PTX20167
品牌ProteoGenix
描述
Anti-Human TEX14 Polyclonal Antibody (PTX20167) is a rabbit polyclonal antibody detecting Sugen kinase 307, Protein kinase-like protein SgK307, SGK307, TEX14, Inactive serine/threonine-protein kinase TEX14, Testis-expressed sequence 14 protein, Testis-expressed sequence 14 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human TEX14 (Cys24-Arg185).
靶标Sugen kinase 307, Protein kinase-like protein SgK307, SGK307, TEX14, Inactive serine/threonine-protein kinase TEX14, Testis-expressed sequence 14 protein, Testis-expressed sequence 14
纯化方式Purified by antigen affinity column.
Accession号Q8IWB6
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Inactive serine/threonine-protein kinase TEX14 is a ~167 kDa protein. Required both for the formation of intercellular bridges during meiosis and for kinetochore-microtubule attachment during mitosis. Intercellular bridges are evolutionarily conserved structures that connect differentiating germ cells and are required for spermatogenesis and male fertility. Acts by promoting the conversion of midbodies into intercellular bridges via its interaction with CEP55: interaction with CEP55 inhibits the interaction between CEP55 and PDCD6IP/ALIX and TSG101, blocking cell abscission and leading to transform midbodies into intercellular bridges. Also plays a role during mitosis: recruited to kinetochores by PLK1 during early mitosis and regulates the maturation of the outer kinetochores and microtubule attachment. Has no protein kinase activity in vitro.

NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-Human TEX14 Polyclonal Antibody

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