

| 货号 | PTX20173 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-Human RGS2 Polyclonal Antibody (PTX20173) is a rabbit polyclonal antibody detecting G0S8, Regulator of G-protein signaling 2, Cell growth-inhibiting gene 31 protein, G0/G1 switch regulatory protein 8, RGS2 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal |
| 同种型 | IgG |
| 免疫原 | E. coli - derived recombinant Human RGS2 (Ser73-Lys201). |
| 靶标 | G0S8, Regulator of G-protein signaling 2, Cell growth-inhibiting gene 31 protein, G0/G1 switch regulatory protein 8, RGS2 |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | P41220 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Regulator of G-protein signaling 2 (RGS2) is a ~24 kDa protein. Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. It is involved in the negative regulation of the angiotensin-activated signaling pathway. Plays a role in the regulation of blood pressure in response to signaling via G protein-coupled receptors and GNAQ. Plays a role in regulating the constriction and relaxation of vascular smooth muscle. 1. Cunningham, ML. et al. (2001) The Journal of biological chemistry 276, 5438-44. PMID: 11063746 2. Kimple, AJ. et al. (2009) The Journal of biological chemistry 284, 19402-11. PMID: 19478087 3. Phan, HTN. et al. (2017) Molecular pharmacology 92, 451-458. PMID: 28784619 4. Nguyen, CH. et al. (2009) The Journal of cell biology 186, 755-65. PMID: 19736320 |
| Note | For research use only. |

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