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Anti-Human PRKG2 Polyclonal Antibody (PTX20201)

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概述
货号PTX20201
品牌ProteoGenix
描述
Anti-Human PRKG2 Polyclonal Antibody (PTX20201) is a rabbit polyclonal antibody detecting cGK2, cGK 2, PRKG2, cGKII, PRKGR2, cGMP-dependent protein kinase II, cGMP-dependent protein kinase 2 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human PRKG2 (Ser431-Phe762).
靶标cGK2, cGK 2, PRKG2, cGKII, PRKGR2, cGMP-dependent protein kinase II, cGMP-dependent protein kinase 2
纯化方式Purified by antigen affinity column.
Accession号Q13237
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

cGMP-dependent protein kinase 2 (PRKG2) is a ~87 kDa protein. Crucial regulator of intestinal secretion and bone growth. Phosphorylates and activates CFTR on the plasma membrane. Plays a key role in intestinal secretion by regulating cGMP-dependent translocation of CFTR in jejunum. Acts downstream of NMDAR to activate the plasma membrane accumulation of GRIA1/GLUR1 in synapse and increase synaptic plasticity. Phosphorylates GRIA1/GLUR1 at Ser-863.

1. Díaz-González, F. et al. (2022) Journal of medical genetics 59, 28-38. PMID: 33106379
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-Human PRKG2 Polyclonal Antibody

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