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Anti-Human ERAP1 Polyclonal Antibody (PTX20237)

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概述
货号PTX20237
品牌ProteoGenix
描述
Anti-Human ERAP1 Polyclonal Antibody (PTX20237) is a rabbit polyclonal antibody detecting Aminopeptidase PILS, ARTS1, Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator, PILS-AP, Endoplasmic reticulum aminopeptidase 1, ARTS-1, A-LAP, Puromycin-insensitive leucyl-specific aminopeptidase, APPILS, ERAP1, KIAA0525, Adipocyte-derived leucine aminopeptidase in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human ERAP1 (Gly529-Met941).
靶标Aminopeptidase PILS, ARTS1, Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator, PILS-AP, Endoplasmic reticulum aminopeptidase 1, ARTS-1, A-LAP, Puromycin-insensitive leucyl-specific aminopeptidase, APPILS, ERAP1, KIAA0525, Adipocyte-derived leucine aminopeptidase
纯化方式Purified by antigen affinity column.
Accession号Q9NZ08
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Endoplasmic reticulum aminopeptidase 1 (ERAP1) is a ~107 kDa protein. Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus, while it has weak activity toward peptides with charged C-terminus.

NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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