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Anti-Human CRHR1 Polyclonal Antibody (PTX20247)

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概述
货号PTX20247
品牌ProteoGenix
描述
Anti-Human CRHR1 Polyclonal Antibody (PTX20247) is a rabbit polyclonal antibody detecting CRH-R1, CRHR1, CRFR, CRFR-1, Corticotropin-releasing factor receptor 1, CRFR1, CRF-R1, CRF-R-1, Corticotropin-releasing hormone receptor 1, CRHR, CRH-R-1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human CRHR1 (Ser24-Lys113).
靶标CRH-R1, CRHR1, CRFR, CRFR-1, Corticotropin-releasing factor receptor 1, CRFR1, CRF-R1, CRF-R-1, Corticotropin-releasing hormone receptor 1, CRHR, CRH-R-1
纯化方式Purified by antigen affinity column.
Accession号P34998
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Corticotropin-releasing factor receptor 1 (CRHR1) is a ~47 kDa protein. G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H.

NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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