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Anti-Human ATP6V1G1 Polyclonal Antibody (PTX20268)

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概述
货号PTX20268
品牌ProteoGenix
描述
Anti-Human ATP6V1G1 Polyclonal Antibody (PTX20268) is a rabbit polyclonal antibody detecting ATP6V1G1, Vacuolar proton pump subunit M16, ATP6G, V-type proton ATPase subunit G 1, Vacuolar proton pump subunit G 1, V-ATPase subunit G 1, V-ATPase 13 kDa subunit 1, ATP6G1, ATP6J in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human ATP6V1G1 (Met1-Gly118).
靶标ATP6V1G1, Vacuolar proton pump subunit M16, ATP6G, V-type proton ATPase subunit G 1, Vacuolar proton pump subunit G 1, V-ATPase subunit G 1, V-ATPase 13 kDa subunit 1, ATP6G1, ATP6J
纯化方式Purified by antigen affinity column.
Accession号O75348
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

V-type proton ATPase subunit G 1 (ATP6V1G1) is a ~13 kDa protein. Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation.

1. Vasanthakumar, T. et al. (2020) Trends in biochemical sciences 45, 295-307. PMID: 32001091
2. Wang, L. et al. (2020) Molecular cell 80, 501-511.e3. PMID: 33065002
3. Miles, AL. et al. (2017) eLife 6. PMID: 28296633
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-Human ATP6V1G1 Polyclonal Antibody

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