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Anti-Human P2RX6 Polyclonal Antibody (PTX20274)

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概述
货号PTX20274
品牌ProteoGenix
描述
Anti-Human P2RX6 Polyclonal Antibody (PTX20274) is a rabbit polyclonal antibody detecting Purinergic receptor, P2XM, Purinergic receptor P2X-like 1, P2RXL1, P2X purinoceptor 6, P2X6, ATP receptor, P2RX6 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human P2RX6 (Lys61-Gly333).
靶标Purinergic receptor, P2XM, Purinergic receptor P2X-like 1, P2RXL1, P2X purinoceptor 6, P2X6, ATP receptor, P2RX6
纯化方式Purified by antigen affinity column.
Accession号O15547
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

P2X purinoceptor 6 (P2RX6) is a ~48 kDa protein. May act as a modulatory subunit rather than a functional channel. Unlike other P2XRs members, P2RX6 does not seem to form functional homotrimers. P2RX6 requires the presence of P2RX4 or P2RX2 to shuttle it to the plasma membrane where it may form functional heterotrimeric receptors at the plasma membrane. P2RX6 can be translocated to the nucleus and functions as a nuclear regulator of post-transcriptional modifications in neurons.

1. Hausmann, R. et al. (2012) The Journal of biological chemistry 287, 13930-43. PMID: 22378790
NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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