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Anti-KYAT1 Polyclonal Antibody (PTX20305)

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概述
货号PTX20305
品牌ProteoGenix
描述
Anti-KYAT1 Polyclonal Antibody (PTX20305) is a rabbit polyclonal antibody detecting KATI, Cysteine-S-conjugate beta-lyase, Glutamine--phenylpyruvate transaminase, Kynurenine--oxoglutarate transaminase 1, Kynurenine--oxoglutarate transaminase I, KYAT1, Kynurenine aminotransferase 1, CCBL1, GTK, Glutamine transaminase K, Kynurenine aminotransferase I in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human KYAT1 (Met1-Leu372).
靶标KATI, Cysteine-S-conjugate beta-lyase, Glutamine--phenylpyruvate transaminase, Kynurenine--oxoglutarate transaminase 1, Kynurenine--oxoglutarate transaminase I, KYAT1, Kynurenine aminotransferase 1, CCBL1, GTK, Glutamine transaminase K, Kynurenine aminotransferase I
纯化方式Purified by antigen affinity column.
Accession号Q16773
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Kynurenine--oxoglutarate transaminase 1 (KYAT1) is a ~47 kDa protein. Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an intermediate in the tryptophan catabolic pathway which is also a broad spectrum antagonist of the three ionotropic excitatory amino acid receptors among others. Also metabolizes the cysteine conjugates of certain halogenated alkenes and alkanes to form reactive metabolites. Catalyzes the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond.

1. Han, Q. et al. (2009) Journal of medicinal chemistry 52, 2786-93. PMID: 19338303
2. Nadvi, NA. et al. (2017) Protein science : a publication of the Protein Society 26, 727-736. PMID: 28097769
3. Perry, S. et al. (1995) FEBS letters 360, 277-80. PMID: 7883047
NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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