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Anti-TRPC6 Polyclonal Antibody (PTX20362)

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概述
货号PTX20362
品牌ProteoGenix
描述
Anti-TRPC6 Polyclonal Antibody (PTX20362) is a rabbit polyclonal antibody detecting TrpC6, TRP-6, Short transient receptor potential channel 6, Transient receptor protein 6, TRP6, TRPC6 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human TRPC6 (Met1-Leu192).
靶标TrpC6, TRP-6, Short transient receptor potential channel 6, Transient receptor protein 6, TRP6, TRPC6
纯化方式Purified by antigen affinity column.
Accession号Q9Y210
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Short transient receptor potential channel 6 (TRPC6) is a ~106 kDa protein. Forms a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C. Does not seem to be activated by intracellular calcium store depletion.

1. Heeringa, SF. et al. (2009) PloS one 4, e7771. PMID: 19936226
2. Hofstra, JM. et al. (2013) Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 28, 1830-8. PMID: 23291369
3. Riehle, M. et al. (2016) Journal of the American Society of Nephrology : JASN 27, 2771-83. PMID: 26892346
4. Hofmann, T. et al. (1999) Nature 397, 259-63. PMID: 9930701
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-TRPC6 Polyclonal Antibody

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