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Anti-Human IL17RC Polyclonal Antibody (PTX20380)

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概述
货号PTX20380
品牌ProteoGenix
描述
Anti-Human IL17RC Polyclonal Antibody (PTX20380) is a rabbit polyclonal antibody detecting IL-17RC, IL-17RL, ZcytoR14, Interleukin-17 receptor C, Interleukin-17 receptor homolog, IL17Rhom, IL17RC, IL-17 receptor C, Interleukin-17 receptor-like protein in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human IL17RC (Asn257-Asn477).
靶标IL-17RC, IL-17RL, ZcytoR14, Interleukin-17 receptor C, Interleukin-17 receptor homolog, IL17Rhom, IL17RC, IL-17 receptor C, Interleukin-17 receptor-like protein
纯化方式Purified by antigen affinity column.
Accession号Q8NAC3
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Interleukin-17 receptor C (IL17RC) is a ~86 kDa protein. Receptor for IL17A and IL17F, major effector cytokines of innate and adaptive immune system involved in antimicrobial host defense and maintenance of tissue integrity. Receptor for IL17A and IL17F, major effector cytokines of innate and adaptive immune system involved in antimicrobial host defense and maintenance of tissue integrity. Receptor for IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RA. Receptor for the heterodimer formed by IL17A and IL17B as part of a heterodimeric complex with IL17RA. Has also been shown to be the cognate receptor for IL17F and to bind IL17A with high affinity without the need for IL17RA.

1. Toy, D. et al. (2006) Journal of immunology (Baltimore, Md. : 1950) 177, 36-9. PMID: 16785495
2. Wright, JF. et al. (2008) Journal of immunology (Baltimore, Md. : 1950) 181, 2799-805. PMID: 18684971
3. Kuestner, RE. et al. (2007) Journal of immunology (Baltimore, Md. : 1950) 179, 5462-73. PMID: 17911633
4. Goepfert, A. et al. (2020) Immunity 52, 499-512.e5. PMID: 32187518
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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