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Anti-IMPDH2 Polyclonal Antibody (PTX20401)

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概述
货号PTX20401
品牌ProteoGenix
描述
Anti-IMPDH2 Polyclonal Antibody (PTX20401) is a rabbit polyclonal antibody detecting IMPDH-II, IMPD 2, IMPD2, IMPDH2, IMPDH 2, Inosine-5'-monophosphate dehydrogenase 2, IMP dehydrogenase 2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human IMPDH2 (Asp226-Phe514).
靶标IMPDH-II, IMPD 2, IMPD2, IMPDH2, IMPDH 2, Inosine-5'-monophosphate dehydrogenase 2, IMP dehydrogenase 2
纯化方式Purified by antigen affinity column.
Accession号P12268
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) is a ~55 kDa protein. Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.

1. Hager, PW. et al. (1995) Biochemical pharmacology 49, 1323-9. PMID: 7763314
2. Carr, SF. et al. (1993) The Journal of biological chemistry 268, 27286-90. PMID: 7903306
3. McLean, JE. et al. (2004) The Biochemical journal 379, 243-51. PMID: 14766016
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-IMPDH2 Polyclonal Antibody

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