

| 货号 | PTX20429 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-HTRA1 Polyclonal Antibody (PTX20429) is a rabbit polyclonal antibody detecting High-temperature requirement A serine peptidase 1, Serine protease 11, HTRA1, PRSS11, HTRA, Serine protease HTRA1, L56 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
|
| 种属反应性 | Human, Mouse, Rat |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 同种型 | IgG |
| 克隆类型 | Polyclonal |
| 免疫原 | E. coli - derived recombinant Human HTRA1 (Gly204-Leu364). |
| 靶标 | High-temperature requirement A serine peptidase 1, Serine protease 11, HTRA1, PRSS11, HTRA, Serine protease HTRA1, L56 |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | Q92743 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Serine protease HTRA1 (PRSS11) is a ~51 kDa protein. Serine protease with a variety of targets, including extracellular matrix proteins such as fibronectin. HTRA1-generated fibronectin fragments further induce synovial cells to up-regulate MMP1 and MMP3 production. May also degrade proteoglycans, such as aggrecan, decorin and fibromodulin. Through cleavage of proteoglycans, may release soluble FGF-glycosaminoglycan complexes that promote the range and intensity of FGF signals in the extracellular space. Regulates the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. |
| Note | For research use only. |

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