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Anti-Human PLCZ1 Polyclonal Antibody (PTX20440)

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概述
货号PTX20440
品牌ProteoGenix
描述
Anti-Human PLCZ1 Polyclonal Antibody (PTX20440) is a rabbit polyclonal antibody detecting 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1, PLCZ1, Testis-development protein NYD-SP27, Phospholipase C-zeta-1, Phosphoinositide phospholipase C-zeta-1, PLC-zeta-1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human PLCZ1 (Ser469-Thr572).
靶标1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1, PLCZ1, Testis-development protein NYD-SP27, Phospholipase C-zeta-1, Phosphoinositide phospholipase C-zeta-1, PLC-zeta-1
纯化方式Purified by antigen affinity column.
Accession号Q86YW0
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 (PLCZ1) is a ~70 kDa protein. The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca(2+)-dependent manner. Triggers intracellular Ca(2+) oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg-activating soluble sperm factor that is transferred from the sperm into the egg cytoplasm following gamete membrane fusion. May exert an inhibitory effect on phospholipase-C-coupled processes that depend on calcium ions and protein kinase C, including CFTR trafficking and function.

NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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