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Anti-SLC12A3 Polyclonal Antibody (PTX20444)

概述
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参考文献

概述

货号	PTX20444
品牌	ProteoGenix
描述	Anti-SLC12A3 Polyclonal Antibody (PTX20444) is a rabbit polyclonal antibody detecting TSC, SLC12A3, NCC, Solute carrier family 12 member 3, Na-Cl cotransporter, Thiazide-sensitive sodium-chloride cotransporter, Na-Cl symporter in ELISA, IHC, WB. Suitable for Human, Mouse, Rat. Highlights Affinity Purified — Minimal background and high purity for reliable results. Multi-Application — Validated across multiple applications. Multi-Species — Cross-reactive for translational research.
种属反应性	Human, Mouse, Rat
应用	ELISA, IHC, WB
宿主	Rabbit
克隆类型	Polyclonal
同种型	IgG
免疫原	E. coli - derived recombinant Human SLC12A3 (Glu3-Cys146).
靶标	TSC, SLC12A3, NCC, Solute carrier family 12 member 3, Na-Cl cotransporter, Thiazide-sensitive sodium-chloride cotransporter, Na-Cl symporter
纯化方式	Purified by antigen affinity column.
Accession号	P55017
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	Solute carrier family 12 member 3 (SLC12A3) is a ~113 kDa protein. Electroneutral sodium and chloride ion cotransporter, which acts as a key mediator of sodium and chloride reabsorption in kidney distal convoluted tubules. Also acts as a receptor for the pro-inflammatory cytokine IL18, thereby contributing to IL18-induced cytokine production, including IFNG, IL6, IL18 and CCL2. May act either independently of IL18R1, or in a complex with IL18R1. 1. Richardson, C. et al. (2008) Journal of cell science 121, 675-84. PMID: 18270262 2. Cruz-Rangel, S. et al. (2011) American journal of physiology. Cell physiology 301, C601-8. PMID: 21613606 3. Glaudemans, B. et al. (2012) European journal of human genetics : EJHG 20, 263-70. PMID: 22009145 4. Nan, J. et al. (2022) Science advances 8, eadd7176. PMID: 36351028 5. Fan, M. et al. (2023) Nature 614, 788-793. PMID: 36792826
Note	For research use only.

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参考文献

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

=

浓度

×

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

×

V₁ (起始体积)

=

工作液

C₂ (终浓度)

×

V₂ (终体积)

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Anti-SLC12A3 Polyclonal Antibody

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