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Anti-ABCG4 Polyclonal Antibody (PTX20449)

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概述
货号PTX20449
品牌ProteoGenix
描述
Anti-ABCG4 Polyclonal Antibody (PTX20449) is a rabbit polyclonal antibody detecting ATP-binding cassette sub-family G member 4, ABCG4, WHITE2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human ABCG4 (Val59-Thr301).
靶标ATP-binding cassette sub-family G member 4, ABCG4, WHITE2
纯化方式Purified by antigen affinity column.
Accession号Q9H172
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

ATP-binding cassette sub-family G member 4 (ABCG4) is a ~71 kDa protein. ATP-dependent transporter of the ATP-binding cassette (ABC) family that may be involved in the cellular efflux of sterols, in particular cholesterol and desmosterol (a cholesterol precursor), to high-density lipoprotein (HDL). May play an important role in the removal of amyloid-beta peptides from brain, in a process that can be antagonized by desmosterol. However it is unclear whether ABCG4 can directly transport amyloid-beta peptides or whether peptide export may be facilitated due to changes in the membrane lipid environment. Induces apoptosis in various cells.

1. Cserepes, J. et al. (2004) Biochemical and biophysical research communications 320, 860-7. PMID: 15240127
2. Yang, A. et al. (2021) Biochimica et biophysica acta. General subjects 1865, 129769. PMID: 33141061
3. Hegyi, Z. et al. (2016) PloS one 11, e0156516. PMID: 27228027
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-ABCG4 Polyclonal Antibody

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