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Anti-Human PDE2A Polyclonal Antibody (PTX20466)

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概述
货号PTX20466
品牌ProteoGenix
描述
Anti-Human PDE2A Polyclonal Antibody (PTX20466) is a rabbit polyclonal antibody detecting cGMP-dependent 3',5'-cyclic phosphodiesterase, CGS-PDE, PDE2A, cGSPDE, Cyclic GMP-stimulated phosphodiesterase in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human PDE2A (Asp241-Gln387).
靶标cGMP-dependent 3',5'-cyclic phosphodiesterase, CGS-PDE, PDE2A, cGSPDE, Cyclic GMP-stimulated phosphodiesterase
纯化方式Purified by antigen affinity column.
Accession号O00408
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

cGMP-dependent 3',5'-cyclic phosphodiesterase (PDE2A) is a ~105 kDa protein. cGMP-activated cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a higher efficiency with cGMP compared to cAMP. Plays a role in cell growth and migration.

1. Iffland, A. et al. (2005) Biochemistry 44, 8312-25. PMID: 15938621
2. Salpietro, V. et al. (2018) Movement disorders : official journal of the Movement Disorder Society 33, 482-488. PMID: 29392776
3. Rosman, GJ. et al. (1997) Gene 191, 89-95. PMID: 9210593
4. Hiramoto, K. et al. (2014) Cellular signalling 26, 1807-17. PMID: 24705027
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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