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Anti-ADCY5 Polyclonal Antibody (PTX20477)

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概述
货号PTX20477
品牌ProteoGenix
描述
Anti-ADCY5 Polyclonal Antibody (PTX20477) is a rabbit polyclonal antibody detecting AC5, ATP pyrophosphate-lyase 5, Adenylate cyclase type 5, Adenylate cyclase type V, Adenylyl cyclase 5, ADCY5 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human ADCY5 (Ser1066-Ser1261).
靶标AC5, ATP pyrophosphate-lyase 5, Adenylate cyclase type 5, Adenylate cyclase type V, Adenylyl cyclase 5, ADCY5
纯化方式Purified by antigen affinity column.
Accession号O95622
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Adenylate cyclase type 5 (ADCY5) is a ~138 kDa protein. Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Mediates signaling downstream of ADRB1. Regulates the increase of free cytosolic Ca(2+) in response to increased blood glucose levels and contributes to the regulation of Ca(2+)-dependent insulin secretion.

1. Ding, Q. et al. (2004) Molecular pharmacology 66, 921-8. PMID: 15385642
2. Chen, YZ. et al. (2014) Annals of neurology 75, 542-9. PMID: 24700542
3. Brand, CS. et al. (2015) Molecular pharmacology 88, 758-67. PMID: 26206488
4. Hodson, DJ. et al. (2014) Diabetes 63, 3009-21. PMID: 24740569
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-ADCY5 Polyclonal Antibody

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