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Anti-ABCD3 Polyclonal Antibody (PTX20505)

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概述
货号PTX20505
品牌ProteoGenix
描述
Anti-ABCD3 Polyclonal Antibody (PTX20505) is a rabbit polyclonal antibody detecting ABCD3, 70 kDa peroxisomal membrane protein, ATP-binding cassette sub-family D member 3, PXMP1, PMP70 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human ABCD3 (Pro425-Ser659).
靶标ABCD3, 70 kDa peroxisomal membrane protein, ATP-binding cassette sub-family D member 3, PXMP1, PMP70
纯化方式Purified by antigen affinity column.
Accession号P28288
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

ATP-binding cassette sub-family D member 3 (ABCD3) is a ~75 kDa protein. Broad substrate specificity ATP-dependent transporter of the ATP-binding cassette (ABC) family that catalyzes the transport of long-chain fatty acids (LCFA)-CoA, dicarboxylic acids-CoA, long-branched-chain fatty acids-CoA and bile acids from the cytosol to the peroxisome lumen for beta-oxydation. Has fatty acyl-CoA thioesterase and ATPase activities. Probably hydrolyzes fatty acyl-CoAs into free fatty acids prior to their ATP-dependent transport into peroxisomes. Thus, play a role in regulation of LCFAs and energy metabolism namely, in the degradation and biosynthesis of fatty acids by beta-oxidation.

1. Roerig, P. et al. (2001) FEBS letters 492, 66-72. PMID: 11248239
2. van Roermund, CW. et al. (2014) Biochimica et biophysica acta 1841, 563-8. PMID: 24333844
3. Ferdinandusse, S. et al. (2015) Human molecular genetics 24, 361-70. PMID: 25168382
4. Okamoto, T. et al. (2018) Biochemical and biophysical research communications 496, 1122-1127. PMID: 29397936
5. Vaca Jacome, AS. et al. (2015) Proteomics 15, 2519-24. PMID: 25944712
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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