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Anti-Human TCIRG1 Polyclonal Antibody (PTX20524)

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概述
货号PTX20524
品牌ProteoGenix
描述
Anti-Human TCIRG1 Polyclonal Antibody (PTX20524) is a rabbit polyclonal antibody detecting TCIRG1, Vacuolar proton translocating ATPase 116 kDa subunit a isoform 3, V-ATPase 116 kDa subunit a3, V-type proton ATPase 116 kDa subunit a3, ATP6V0A3, ATP6N1C, Osteoclastic proton pump 116 kDa subunit, TIRC7, T-cell immune response cDNA7 protein, T-cell immune regulator 1, OC-116 kDa, OC116 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human TCIRG1 (Met1-Glu385).
靶标TCIRG1, Vacuolar proton translocating ATPase 116 kDa subunit a isoform 3, V-ATPase 116 kDa subunit a3, V-type proton ATPase 116 kDa subunit a3, ATP6V0A3, ATP6N1C, Osteoclastic proton pump 116 kDa subunit, TIRC7, T-cell immune response cDNA7 protein, T-cell immune regulator 1, OC-116 kDa, OC116
纯化方式Purified by antigen affinity column.
Accession号Q13488
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

V-type proton ATPase 116 kDa subunit a 3 (TCIRG1/TIRC7) is a ~92 kDa protein. Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Seems to be directly involved in T-cell activation.

1. Heinemann, T. et al. (1999) Genomics 57, 398-406. PMID: 10329006
NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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