

| 货号 | PTX20577 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-Mouse CD105/ENG Polyclonal Antibody (PTX20577) is a rabbit polyclonal antibody detecting Endoglin (Cell surface MJ7/18 antigen) (CD antigen CD105) in ELISA, IHC, WB. Suitable for Mouse.
Highlights
|
| 种属反应性 | Mouse |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 同种型 | IgG |
| 克隆类型 | Polyclonal |
| 免疫原 | E. coli - derived recombinant Mouse CD105/ENG (Asp37-Gly332). |
| 靶标 | Endoglin (Cell surface MJ7/18 antigen) (CD antigen CD105) |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | Q63961 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Endoglin (CD105/ENG) is a ~70 kDa protein. Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature. Regulates the migration of vascular endothelial cells. Required for normal extraembryonic angiogenesis and for embryonic heart development. May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis. 1. Arthur, HM. et al. (2000) Developmental biology 217, 42-53. PMID: 10625534 2. Lee, NY. et al. (2007) The Journal of biological chemistry 282, 21507-17. PMID: 17540773 3. Sugden, WW. et al. (2017) Nature cell biology 19, 653-665. PMID: 28530658 4. Nolan-Stevaux, O. et al. (2012) PloS one 7, e50920. PMID: 23300529 |
| Note | For research use only. |

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