

| 货号 | PTX20579 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-Mouse EPOR Polyclonal Antibody (PTX20579) is a rabbit polyclonal antibody detecting Erythropoietin receptor (EPO-R) in ELISA, IHC, WB. Suitable for Mouse.
Highlights
|
| 种属反应性 | Mouse |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal |
| 同种型 | IgG |
| 免疫原 | E. coli - derived recombinant Mouse EPOR (Asp32-Thr243). |
| 靶标 | Erythropoietin receptor (EPO-R) |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | P14753 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Erythropoietin receptor (EPOR) is a ~55 kDa protein. Receptor for erythropoietin, which mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase. 1. D'Andrea, AD. et al. (1989) Cell 57, 277-85. PMID: 2539263 2. Sawyer, ST. et al. (1993) Proceedings of the National Academy of Sciences of the United States of America 90, 6849-53. PMID: 8341708 3. Miura, O. et al. (1993) Molecular and cellular biology 13, 1788-95. PMID: 8382775 4. Hilton, DJ. et al. (1996) The Journal of biological chemistry 271, 4699-708. PMID: 8617735 5. Chin, H. et al. (1998) Blood 91, 3734-45. PMID: 9573010 |
| Note | For research use only. |

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