

| 货号 | PTX19950 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-Human SOS1 Polyclonal Antibody (PTX19950) is a rabbit polyclonal antibody detecting SOS1, Son of sevenless homolog 1, SOS-1 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal |
| 同种型 | IgG |
| 免疫原 | E. coli - derived recombinant Human SOS1 (Gln566-Arg1046). |
| 靶标 | SOS1, Son of sevenless homolog 1, SOS-1 |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | Q07889 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Son of sevenless homolog 1 (SOS1) is a ~152 kDa protein. Promotes the exchange of Ras-bound GDP by GTP. Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3/ERK1 in response to EGF. Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor (GEF) activity. 1. Chardin, P. et al. (1993) Science (New York, N.Y.) 260, 1338-43. PMID: 8493579 2. Modzelewska, K. et al. (2007) Molecular and cellular biology 27, 3695-707. PMID: 17339331 |
| Note | For research use only. |

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