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Anti-Mouse FABP5 Polyclonal Antibody (PTX19992)

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概述
货号PTX19992
品牌ProteoGenix
描述
Anti-Mouse FABP5 Polyclonal Antibody (PTX19992) is a rabbit polyclonal antibody detecting Psoriasis-associated fatty acid-binding protein homolog, FABP5, E-FABP, Epidermal-type fatty acid-binding protein, Fatty acid-binding protein, epidermal, Fatty acid-binding protein 5, PA-FABP in ELISA, IHC, WB. Suitable for Mouse.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Mouse
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Mouse FABP5 (Met1-Gln135).
靶标Psoriasis-associated fatty acid-binding protein homolog, FABP5, E-FABP, Epidermal-type fatty acid-binding protein, Fatty acid-binding protein, epidermal, Fatty acid-binding protein 5, PA-FABP
纯化方式Purified by antigen affinity column.
Accession号Q05816
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Fatty acid-binding protein 5 (FABP5) is a ~15 kDa protein. Intracellular carrier for long-chain fatty acids and related active lipids, such as endocannabinoids, that regulate the metabolism and actions of the ligands they bind. In addition to the cytosolic transport, selectively delivers specific fatty acids from the cytosol to the nucleus, wherein they activate nuclear receptors. Delivers retinoic acid to the nuclear receptor peroxisome proliferator-activated receptor delta; which promotes proliferation and survival. May also serve as a synaptic carrier of endocannabinoid at central synapses and thus controls retrograde endocannabinoid signaling. Modulates inflammation by regulating PTGES induction via NF-kappa-B activation, and prostaglandin E2 (PGE2) biosynthesis during inflammation.

1. Maeda, K. et al. (2003) Diabetes 52, 300-7. PMID: 12540600
2. Kane, CD. et al. (1996) Biochemistry 35, 2894-900. PMID: 8608126
3. Schug, TT. et al. (2007) Cell 129, 723-33. PMID: 17512406
4. Haj-Dahmane, S. et al. (2018) Proceedings of the National Academy of Sciences of the United States of America 115, 3482-3487. PMID: 29531087
5. Bogdan, D. et al. (2018) The Journal of biological chemistry 293, 5295-5306. PMID: 29440395
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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