

| 货号 | PTX19115 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-LASV GPC Antibody (25.6A) [25.6A] (PTX19115) is a human monoclonal antibody detecting Pre-glycoprotein polyprotein GP complex, Pre-GP-C, GPC, GP-C in ELISA, Neutralization. Suitable for Lassa virus (strain Mouse/Sierra Leone/Josiah/1976) (LASV).
Highlights
|
| 种属反应性 | Lassa virus (strain Mouse/Sierra Leone/Josiah/1976) (LASV) |
| 应用 | ELISA, Neutralization |
| 宿主 | Human |
| 同种型 | IgG1, kappa |
| 克隆号 | 25.6A |
| 克隆类型 | Monoclonal |
| 靶标 | Pre-glycoprotein polyprotein GP complex, Pre-GP-C, GPC, GP-C |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >95% as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | P08669 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 背景 | Pre-glycoprotein polyprotein GP complex (GPC) is a ~55 kDa protein. Functions as a cleaved signal peptide that is retained as the third component of the GP complex (GP-C). Helps to stabilize the spike complex in its native conformation. The SSP is required for efficient glycoprotein expression, post-translational maturation cleavage of G1 and G2, glycoprotein transport to the cell surface plasma membrane, formation of infectious virus particles, and acid pH-dependent glycoprotein-mediated cell fusion. 1. Katz, M. et al. (2022) Nature 603, 174-179. PMID: 35173332 2. Eichler, R. et al. (2003) EMBO reports 4, 1084-8. PMID: 14555961 |
| Note | For research use only. |

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