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Anti-LASV GPC Antibody (36.9F) (PTX19117)

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概述
货号PTX19117
品牌ProteoGenix
描述
Anti-LASV GPC Antibody (36.9F) [36.9F] (PTX19117) is a human monoclonal antibody detecting Pre-glycoprotein polyprotein GP complex, Pre-GP-C, GPC, GP-C in ELISA, Neutralization. Suitable for Lassa virus (strain Mouse/Sierra Leone/Josiah/1976) (LASV).
Highlights
  • Protein A/G purified from cell culture supernatant. — Ensuring high specificity and minimal background.
  • Multi-Application — Validated across multiple applications.
种属反应性Lassa virus (strain Mouse/Sierra Leone/Josiah/1976) (LASV)
应用ELISA, Neutralization
宿主Human
同种型IgG1, kappa
克隆号36.9F
克隆类型Monoclonal
靶标Pre-glycoprotein polyprotein GP complex, Pre-GP-C, GPC, GP-C
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P08669
状态Liquid
保存溶液 0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Pre-glycoprotein polyprotein GP complex (GPC) is a ~55 kDa protein. Functions as a cleaved signal peptide that is retained as the third component of the GP complex (GP-C). Helps to stabilize the spike complex in its native conformation. The SSP is required for efficient glycoprotein expression, post-translational maturation cleavage of G1 and G2, glycoprotein transport to the cell surface plasma membrane, formation of infectious virus particles, and acid pH-dependent glycoprotein-mediated cell fusion.

1. Katz, M. et al. (2022) Nature 603, 174-179. PMID: 35173332
2. Eichler, R. et al. (2003) EMBO reports 4, 1084-8. PMID: 14555961
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-LASV GPC Antibody (36.9F)

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