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Anti-Mouse DKK1 Antibody (MOR04454) (PTX19173)

概述
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概述

货号	PTX19173
品牌	ProteoGenix
描述	Anti-Mouse DKK1 Antibody (MOR04454) [MOR04454] (PTX19173) is a rat monoclonal antibody detecting Dickkopf-1, SK, hDkk-1, Dkk-1, Dickkopf-related protein 1, DKK1 in ELISA. Suitable for Human, Mouse. Highlights Protein A/G purified from cell culture supernatant. — Ensuring high specificity and minimal background. Validated for ELISA — Optimized for consistent performance. Multi-Species — Cross-reactive for translational research.
种属反应性	Human, Mouse
应用	ELISA
宿主	Rat
克隆类型	Monoclonal
同种型	IgG1, kappa
克隆号	MOR04454
靶标	Dickkopf-1, SK, hDkk-1, Dkk-1, Dickkopf-related protein 1, DKK1
内毒素水平	Please contact with the lab for this information.
纯度	>95% as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	O54908
状态	Liquid
保存溶液	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景	Dickkopf-related protein 1 (DKK1) is a ~29 kDa protein. Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independent manner, and has anti-apoptotic activity. Plays a role in limb development; attenuates Wnt signaling in the developing limb to allow normal limb patterning. 1. Chen, L. et al. (2008) The Journal of biological chemistry 283, 23364-70. PMID: 18524778 2. Causeret, F. et al. (2016) Cell death and differentiation 23, 323-32. PMID: 26206087 3. Ellwanger, K. et al. (2008) Molecular and cellular biology 28, 4875-82. PMID: 18505822
Note	For research use only.

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公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

=

浓度

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体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

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V₁ (起始体积)

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工作液

C₂ (终浓度)

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V₂ (终体积)

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Anti-Mouse DKK1 Antibody (MOR04454)

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