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Anti-Mouse KIRREL3/NEPH2 Antibody (N321C/49R) (PTX19248)

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概述
货号PTX19248
品牌ProteoGenix
描述
Anti-Mouse KIRREL3/NEPH2 Antibody (N321C/49R) [N321C/49R] (PTX19248) is a mouse monoclonal antibody detecting KIRREL3, NEPH2, Kin of irregular chiasm-like protein 3, Nephrin-like protein 2, KIAA1867, Kin of IRRE-like protein 3 in IF, IHC, WB. Suitable for Mouse, Rat.
Highlights
  • Protein A/G purified from cell culture supernatant. — Ensuring high specificity and minimal background.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Mouse, Rat
应用IF, IHC, WB
宿主Mouse
克隆类型Monoclonal
同种型IgG2a, kappa
克隆号N321C/49R
靶标KIRREL3, NEPH2, Kin of irregular chiasm-like protein 3, Nephrin-like protein 2, KIAA1867, Kin of IRRE-like protein 3
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号Q8BR86,Q09GS6
状态Liquid
保存溶液 0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Kin of IRRE-like protein 3 (KIRREL3/NEPH2) is a ~85 kDa protein. Synaptic adhesion molecule required for the formation of target-specific synapses. Required for formation of target-specific synapses at hippocampal mossy fiber synapses. Required for formation of mossy fiber filopodia, the synaptic structures connecting dentate granule and GABA neurons. Probably acts as a homophilic adhesion molecule that promotes trans-cellular interactions and stabilize mossy fiber filipodia contact and subsequent synapse formation. Required for the coalescence of vomeronasal sensory neuron axons.

1. Prince, JE. et al. (2013) Development (Cambridge, England) 140, 2398-408. PMID: 23637329
2. Martin, EA. et al. (2015) eLife 4, e09395. PMID: 26575286
3. Ueno, H. et al. (2003) Nature immunology 4, 457-63. PMID: 12665856
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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