

| 货号 | PTX19248 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-Mouse KIRREL3/NEPH2 Antibody (N321C/49R) [N321C/49R] (PTX19248) is a mouse monoclonal antibody detecting KIRREL3, NEPH2, Kin of irregular chiasm-like protein 3, Nephrin-like protein 2, KIAA1867, Kin of IRRE-like protein 3 in IF, IHC, WB. Suitable for Mouse, Rat.
Highlights
|
| 种属反应性 | Mouse, Rat |
| 应用 | IF, IHC, WB |
| 宿主 | Mouse |
| 克隆类型 | Monoclonal |
| 同种型 | IgG2a, kappa |
| 克隆号 | N321C/49R |
| 靶标 | KIRREL3, NEPH2, Kin of irregular chiasm-like protein 3, Nephrin-like protein 2, KIAA1867, Kin of IRRE-like protein 3 |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >95% as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | Q8BR86,Q09GS6 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 背景 | Kin of IRRE-like protein 3 (KIRREL3/NEPH2) is a ~85 kDa protein. Synaptic adhesion molecule required for the formation of target-specific synapses. Required for formation of target-specific synapses at hippocampal mossy fiber synapses. Required for formation of mossy fiber filopodia, the synaptic structures connecting dentate granule and GABA neurons. Probably acts as a homophilic adhesion molecule that promotes trans-cellular interactions and stabilize mossy fiber filipodia contact and subsequent synapse formation. Required for the coalescence of vomeronasal sensory neuron axons. 1. Prince, JE. et al. (2013) Development (Cambridge, England) 140, 2398-408. PMID: 23637329 2. Martin, EA. et al. (2015) eLife 4, e09395. PMID: 26575286 3. Ueno, H. et al. (2003) Nature immunology 4, 457-63. PMID: 12665856 |
| Note | For research use only. |

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