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Anti-Human VAP-1/AOC3 Antibody (TK8-14) (PTX19260)

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概述
货号PTX19260
品牌ProteoGenix
描述
Anti-Human VAP-1/AOC3 Antibody (TK8-14) [TK8-14] (PTX19260) is a mouse monoclonal antibody detecting Membrane primary amine oxidase, AOC3, SSAO, Semicarbazide-sensitive amine oxidase, Vascular adhesion protein 1, VAP-1, HPAO, Copper amine oxidase, VAP1 in ELISA, FCM, IF, IHC, IP, WB. Suitable for Human.
Highlights
  • Protein A/G purified from cell culture supernatant. — Ensuring high specificity and minimal background.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, FCM, IF, IHC, IP, WB
宿主Mouse
克隆类型Monoclonal
同种型IgG2a, kappa
克隆号TK8-14
靶标Membrane primary amine oxidase, AOC3, SSAO, Semicarbazide-sensitive amine oxidase, Vascular adhesion protein 1, VAP-1, HPAO, Copper amine oxidase, VAP1
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号Q16853
状态Liquid
保存溶液 0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Amine oxidase [copper-containing] 3 (AOC3/VAP-1) is a ~84 kDa protein. Catalyzes the oxidative deamination of primary amines to the corresponding aldehydes with the concomitant production of hydrogen peroxide and ammonia. Has a preference for the primary monoamines methylamine and benzylamine. Could also act on 2-phenylethylamine but much less efficiently. At endothelial cells surface can also function as a cell adhesion protein that participates in lymphocyte extravasation and recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion.

1. Kaitaniemi, S. et al. (2009) Cellular and molecular life sciences : CMLS 66, 2743-57. PMID: 19588076
2. Bligt-Lindén, E. et al. (2013) Journal of medicinal chemistry 56, 9837-48. PMID: 24304424
3. Smith, DJ. et al. (1998) The Journal of experimental medicine 188, 17-27. PMID: 9653080
4. Salmi, M. et al. (1997) The Journal of experimental medicine 186, 589-600. PMID: 9254657
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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