

| 货号 | PTX19355 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-Influenza A virus M/Matrix protein 2 Antibody (14C2) (PTX19355) Purity: >95% as determined by SDS-PAGE..
Highlights
|
| 种属反应性 | Influenza A virus (strain A/Puerto Rico/8/1934 H1N1) |
| 应用 | ELISA, IF, WB |
| 宿主 | Mouse |
| 同种型 | IgG1-kappa |
| 克隆号 | 14C2 |
| 克隆类型 | Monoclonal |
| 靶标 | Matrix protein 2, Proton channel protein M2, M |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >95% as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | P06821 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 背景 | Matrix protein 2 is a ~11 kDa protein. Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry. After attaching to the cell surface, the virion enters the cell by endocytosis. Acidification of the endosome triggers M2 ion channel activity. The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur. Also plays a role in viral proteins secretory pathway. |
| Note | For research use only. |





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