

| 货号 | PTX19399 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-MARV GP/Envelope glycoprotein Antibody (MR78) (PTX19399) Purity: >95% as determined by SDS-PAGE..
Highlights
|
| 种属反应性 | Lake Victoria marburgvirus (strain Ravn-87) (MARV) (Marburg virus (strainKenya/Ravn/1987)) |
| 应用 | ELISA |
| 宿主 | Human |
| 同种型 | IgG1 |
| 克隆号 | MR78 |
| 克隆类型 | Monoclonal |
| 靶标 | Envelope glycoprotein, GP1,2, GP, Virion spike glycoprotein, GP1, GP2, GP |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >95% as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | Q1PDC7 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 背景 | Envelope glycoprotein (GP) is a ~75 kDa protein. GP1 is responsible for binding to the receptor(s) on target cells. Interacts with CD209/DC-SIGN and CLEC4M/DC-SIGNR which act as cofactors for virus entry into the host cell. Binding to CD209 and CLEC4M, which are respectively found on dendritic cells (DCs), and on endothelial cells of liver sinusoids and lymph node sinuses, facilitate infection of macrophages and endothelial cells. These interactions not only facilitate virus cell entry, but also allow capture of viral particles by DCs and subsequent transmission to susceptible cells without DCs infection (trans infection). |
| Note | For research use only. |

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