Anti-Human GRAMD1C Polyclonal Antibody (HA529014)

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50ug
100ug

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概述
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参考文献
产品说明书

概述

货号

HA529014

品牌

abinScience

描述

Anti-Human GRAMD1C Polyclonal Antibody (HA529014) is a rabbit polyclonal antibody detecting GRAMD1C in WB, IHC, ELISA. Suitable for Human and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human

应用

WB, IHC, ELISA

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human Human GRAMD1C (His326-Trp463).

靶标

GRAMD1C

内毒素水平

Please contact with the lab for this information.

纯度

>90% as determined by SDS-PAGE.

纯化方式

Purified by antigen affinity column.

Accession号

Q8IYS0

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

别名

Protein Aster-C, GRAM domain-containing protein 1C, GRAMD1C

背景

Protein Aster-C (GRAMD1C) is a ~76 kDa protein. Cholesterol transporter that mediates non-vesicular transport of cholesterol from the plasma membrane (PM) to the endoplasmic reticulum (ER). Contains unique domains for binding cholesterol and the PM, thereby serving as a molecular bridge for the transfer of cholesterol from the PM to the ER. Plays a crucial role in cholesterol homeostasis and has the unique ability to localize to the PM based on the level of membrane cholesterol. In lipid-poor conditions localizes to the ER membrane and in response to excess cholesterol in the PM is recruited to the endoplasmic reticulum-plasma membrane contact sites (EPCS) which is mediated by the GRAM domain. At the EPCS, the sterol-binding VASt/ASTER domain binds to the cholesterol in the PM and facilitates its transfer from the PM to ER.

Note

For research use only.

图片

参考文献

产品说明书

Anti-Human GRAMD1C Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human GRAMD1C Polyclonal Antibody (HA529014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human GRAMD1C Polyclonal Antibody (HA529014)

概述

图片

参考文献

产品说明书

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