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Anti-Human GPX2 Polyclonal Antibody (HA536014)

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概述
货号HA536014
品牌abinScience
描述
Anti-Human GPX2 Polyclonal Antibody (HA536014) is a rabbit polyclonal antibody detecting GPX2 in WB, IHC, ELISA. Suitable for Human, Mus musculus, Rattus norvegicus, Callithrix jacchus, and Hylobates lar.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用WB, IHC, ELISA
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human GPX2 (Met1-Ile190).
靶标GPX2
内毒素水平Please contact with the lab for this information.
纯度>90% as determined by SDS-PAGE.
纯化方式Purified by antigen affinity column.
Accession号P18283
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名Glutathione peroxidase 2, GPx-2, GSHPx-2, EC:1.11.1.9, Gastrointestinal glutathione peroxidase, Glutathione peroxidase-gastrointestinal, GPx-GI, GSHPx-GI, Glutathione peroxidase-related protein 2, GPRP-2, Phospholipid hydroperoxide glutathione peroxidase GPX2, EC:1.11.1.12, GPX2
背景

Glutathione peroxidase 2 (GPX2) is a ~21 kDa protein. Catalyzes the reduction of hydroperoxides in a glutathione-dependent manner thus regulating cellular redox homeostasis. Can reduce small soluble hydroperoxides such as H2O2, cumene hydroperoxide and tert-butyl hydroperoxide, as well as several fatty acid-derived hydroperoxides. Cannot reduce phosphatidycholine hydroperoxide.

1. Schwarz, M. et al. (2023) Redox biology 59, 102593. PMID: 36608588
2. Chu, FF. et al. (1993) The Journal of biological chemistry 268, 2571-6. PMID: 8428933
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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