Anti-CIART Polyclonal Antibody (HA556014)

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50ug
100ug

数量：

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概述
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参考文献
产品说明书

概述

货号

HA556014

品牌

abinScience

描述

Anti-CIART Polyclonal Antibody (HA556014) is a rabbit polyclonal antibody detecting CIART in WB, IHC, ELISA. Suitable for Human and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human

应用

WB, IHC, ELISA

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant CIART (Thr113-Gly205).

靶标

CIART

内毒素水平

Please contact with the lab for this information.

纯度

>90% as determined by SDS-PAGE.

纯化方式

Purified by antigen affinity column.

Accession号

Q8N365

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

别名

Circadian-associated transcriptional repressor, ChIP-derived repressor of network oscillator, Chrono, Computationally highlighted repressor of the network oscillator, CIART

背景

Circadian-associated transcriptional repressor (CIART) is a ~41 kDa protein. Transcriptional repressor which forms a negative regulatory component of the circadian clock and acts independently of the circadian transcriptional repressors: CRY1, CRY2 and BHLHE41. In a histone deacetylase-dependent manner represses the transcriptional activator activity of the CLOCK-BMAL1 heterodimer. Abrogates the interaction of BMAL1 with the transcriptional coactivator CREBBP and can repress the histone acetyl-transferase activity of the CLOCK-BMAL1 heterodimer, reducing histone acetylation of its target genes. Rhythmically binds the E-box elements (5'-CACGTG-3') on circadian gene promoters and its occupancy shows circadian oscillation antiphasic to BMAL1. Interacts with the glucocorticoid receptor (NR3C1) and contributes to the repressive function in the glucocorticoid response.

Note

For research use only.

图片

参考文献

产品说明书

Anti-CIART Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-CIART Polyclonal Antibody (HA556014)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-CIART Polyclonal Antibody (HA556014)

概述

图片

参考文献

产品说明书

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