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Anti-Mouse Neuropilin-1/NRP1 Recombinant Antibody (YW64.3) (MT070013)

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规格:
  • 50ug
  • 100ug
  • 1mg
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概述
货号MT070013
品牌abinScience
种属反应性Human, Mouse
应用ELISA, FCM
同种型IgG2a, kappa
克隆号YW64.3
靶标Neuropilin-1, Vascular endothelial cell growth factor 165 receptor, CD304, NRP1, NRP, VEGF165R
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号O14786, P97333
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:2000-1:20000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Neuropilin-1 (CD304/NRP1) is a ~103 kDa protein. Cell-surface receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. Mediates the chemorepulsant activity of semaphorins. Recognizes a C-end rule (CendR) motif R/KXXR/K on its ligands which causes cellular internalization and vascular leakage. It binds to semaphorin 3A, the PLGF-2 isoform of PGF, the VEGF165 isoform of VEGFA and VEGFB. Coexpression with KDR results in increased VEGF165 binding to KDR as well as increased chemotaxis.

1. Gagnon, ML. et al. (2000) Proceedings of the National Academy of Sciences of the United States of America 97, 2573-8. PMID: 10688880
2. He, Z. et al. (1997) Cell 90, 739-51. PMID: 9288753
3. Soker, S. et al. (1998) Cell 92, 735-45. PMID: 9529250
4. Teesalu, T. et al. (2009) Proceedings of the National Academy of Sciences of the United States of America 106, 16157-62. PMID: 19805273
5. Issitt, T. et al. (2019) iScience 11, 205-223. PMID: 30623799
NoteFor research use only
Isotype ControlMouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023)
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Mouse CD304/NRP1 Recombinant Antibody (YW64.3)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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