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Anti-Mouse IL-33 Polyclonal Antibody (MF543014)

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概述
货号MF543014
品牌abinScience
描述
Anti-IL33 Polyclonal Antibody (MF543014) is a rabbit polyclonal antibody detecting Il33 in ELISA, IHC, WB. Suitable for Mus musculus and Rattus norvegicus.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
种属反应性Mouse
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Mouse IL33 (Ser109-Ile266).
靶标Interleukin-33, IL-33, Interleukin-33(102-266), Interleukin-33(109-266), Il33
内毒素水平Please contact with the lab for this information.
纯化方式Purified by antigen affinity column.
Accession号Q8BVZ5, Q66H70
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Interleukin-33 (IL33) is a ~29 kDa protein. Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as an enhancer of polarization of alternatively activated macrophages. Acts as a chemoattractant for Th2 cells, and may function as an 'alarmin', that amplifies immune responses during tissue injury.

1. Osbourn, M. et al. (2017) Immunity 47, 739-751.e5. PMID: 29045903
2. Faas, M. et al. (2021) Immunity 54, 2531-2546.e5. PMID: 34644537
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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