

| 货号 | HA590014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-SURF4 Polyclonal Antibody (HA590014) is a rabbit polyclonal antibody detecting SURF4 in ELISA, IHC, WB. Suitable for Human, Mouse, Bovine, Chicken, and Zebrafish.
Highlights
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| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant human SURF4 (Gly2-Tyr63&Asp113-Ser178). | ||||||||
| 靶标 | Surfeit locus protein 4, SURF4, SURF-4 | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | O15260, Q64310, A7YY49, Q800K9, Q7SZQ7 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Surfeit locus protein 4 (SURF4) is a ~30 kDa protein. Endoplasmic reticulum cargo receptor that mediates the export of lipoproteins by recruiting cargos into COPII vesicles to facilitate their secretion. Acts as a cargo receptor for lipoproteins bearing both APOB and APOA1, thereby regulating lipoprotein delivery and the maintenance of lipid homeostasis. Synergizes with the GTPase SAR1B to mediate transport of circulating lipoproteins. Promotes the secretion of PCSK9. Also mediates the efficient secretion of erythropoietin (EPO). 1. Saegusa, K. et al. (2018) The Journal of cell biology 217, 2073-2085. PMID: 29643117 2. Emmer, BT. et al. (2018) eLife 7. PMID: 30251625 3. Wang, X. et al. (2021) Cell metabolism 33, 350-366.e7. PMID: 33186557 4. Lin, Z. et al. (2020) Molecular and cellular biology 40. PMID: 32989016 5. Mitrovic, S. et al. (2008) Molecular biology of the cell 19, 1976-90. PMID: 18287528 | ||||||||
| Note | For research use only |

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