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Anti-SURF4 Polyclonal Antibody (HA590014)

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概述
货号HA590014
品牌abinScience
描述
Anti-SURF4 Polyclonal Antibody (HA590014) is a rabbit polyclonal antibody detecting SURF4 in ELISA, IHC, WB. Suitable for Human, Mouse, Bovine, Chicken, and Zebrafish.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant human SURF4 (Gly2-Tyr63&Asp113-Ser178).
靶标Surfeit locus protein 4, SURF4, SURF-4
内毒素水平Please contact with the lab for this information.
纯化方式Purified by antigen affinity column.
Accession号O15260, Q64310, A7YY49, Q800K9, Q7SZQ7
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Surfeit locus protein 4 (SURF4) is a ~30 kDa protein. Endoplasmic reticulum cargo receptor that mediates the export of lipoproteins by recruiting cargos into COPII vesicles to facilitate their secretion. Acts as a cargo receptor for lipoproteins bearing both APOB and APOA1, thereby regulating lipoprotein delivery and the maintenance of lipid homeostasis. Synergizes with the GTPase SAR1B to mediate transport of circulating lipoproteins. Promotes the secretion of PCSK9. Also mediates the efficient secretion of erythropoietin (EPO).

1. Saegusa, K. et al. (2018) The Journal of cell biology 217, 2073-2085. PMID: 29643117
2. Emmer, BT. et al. (2018) eLife 7. PMID: 30251625
3. Wang, X. et al. (2021) Cell metabolism 33, 350-366.e7. PMID: 33186557
4. Lin, Z. et al. (2020) Molecular and cellular biology 40. PMID: 32989016
5. Mitrovic, S. et al. (2008) Molecular biology of the cell 19, 1976-90. PMID: 18287528
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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