

| 货号 | JN060026 |
|---|---|
| 品牌 | abinScience |
| 描述 |
Research Grade Anti-ClfA Antibody (AZD7745) [AZD7745] (JN060026) is a human monoclonal antibody detecting Clumping factor A in ELISA, Functional assay, Research in vivo.
Highlights
|
| 种属反应性 | Staphylococcus aureus |
| 应用 | ELISA, Functional assay, Research in vivo |
| 宿主 | Human |
| 同种型 | IgG |
| 克隆号 | AZD7745 |
| 克隆类型 | Monoclonal |
| 靶标 | Clumping factor A, Fibrinogen receptor A, Fibrinogen-binding protein A, clfA |
| 内毒素水平 | < 10 EU/mg |
| 纯度 | >95% as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | Q53653, Q2G015, Q5HHM8 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | SAR114 |
| 背景 | Clumping factor A (ClfA) is a ~97 kDa protein. Cell surface-associated protein implicated in virulence. Promotes bacterial attachment exclusively to the gamma-chain of human fibrinogen. Induces formation of bacterial clumps, which diminish the ability of group IIA phospholipase A2 to cause bacterial phospholipid hydrolysis and killing. Significantly decreases macrophage phagocytosis possibly thanks to the clumps, clumped bacteria being too large to be phagocytosed. Dominant factor responsible for human platelet aggregation, which may be an important mechanism for initiating infective endocarditis. |
| Note | For research use only. |

SDS-PAGE for Research Grade Anti-ClfA Antibody (AZD7745)



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