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Anti-ClfA Reference Antibody (AZD7745, RUO) (JN060026)

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规格:
  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
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  • 参考文献

  • 产品说明书

概述
货号JN060026
品牌abinScience
描述
Research Grade Anti-ClfA Antibody (AZD7745) [AZD7745] (JN060026) is a human monoclonal antibody detecting Clumping factor A in ELISA, Functional assay, Research in vivo.
Highlights
  • Multi-Application — Validated across multiple applications.
种属反应性Staphylococcus aureus
应用ELISA, Functional assay, Research in vivo
宿主Human
同种型IgG
克隆号AZD7745
克隆类型Monoclonal
靶标Clumping factor A, Fibrinogen receptor A, Fibrinogen-binding protein A, clfA
内毒素水平< 10 EU/mg
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号Q53653, Q2G015, Q5HHM8
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名SAR114
背景

Clumping factor A (ClfA) is a ~97 kDa protein. Cell surface-associated protein implicated in virulence. Promotes bacterial attachment exclusively to the gamma-chain of human fibrinogen. Induces formation of bacterial clumps, which diminish the ability of group IIA phospholipase A2 to cause bacterial phospholipid hydrolysis and killing. Significantly decreases macrophage phagocytosis possibly thanks to the clumps, clumped bacteria being too large to be phagocytosed. Dominant factor responsible for human platelet aggregation, which may be an important mechanism for initiating infective endocarditis.

NoteFor research use only.
图片
  • SDS-PAGE

    SDS-PAGE for Research Grade Anti-ClfA Antibody (AZD7745)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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