CCAAT/enhancer-binding protein alpha (CEBPA) is a ~37 kDa protein. Transcription factor that coordinates proliferation arrest and the differentiation of myeloid progenitors, adipocytes, hepatocytes, and cells of the lung and the placenta. Binds directly to the consensus DNA sequence 5'-T[TG]NNGNAA[TG]-3' acting as an activator on distinct target genes. During early embryogenesis, plays essential and redundant functions with CEBPB. Essential for the transition from common myeloid progenitors (CMP) to granulocyte/monocyte progenitors (GMP). Critical for the proper development of the liver and the lung. 1. Wang, GL. et al. (2004) Genes & development 18, 912-25. PMID: 151074043. Zhang, Z. et al. (2022) Cell metabolism 34, 1860-1874.e4. PMID: 362286164. Lin, FT. et al. (1993) Proceedings of the National Academy of Sciences of the United States of America 90, 9606-10. PMID: 84157485. Bégay, V. et al. (2004) Molecular and cellular biology 24, 9744-51. PMID: 155097796. Ohlsson, E. et al. (2014) The Journal of experimental medicine 211, 5-13. PMID: 243670037. Flodby, P. et al. (1996) The Journal of biological chemistry 271, 24753-60. PMID: 87987458. Samuelsson, L. et al. (1991) The EMBO journal 10, 3787-93. PMID: 19359009. Lin, FT. et al. (1994) Proceedings of the National Academy of Sciences of the United States of America 91, 8757-61. PMID: 8090719 | 
