Anti-VAMP8 Polyclonal Antibody (HP094024)

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概述
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参考文献
产品说明书

概述

货号

HP094024

品牌

abinScience

描述

Anti-VAMP8 Polyclonal Antibody (HP094024) is a rabbit polyclonal antibody detecting Vesicle-associated membrane protein 8; VAMP-8; Endobrevin; EDB; VAMP8 in ELISA, IHC, WB. Suitable for Human, Rat, Bovine, and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant human VAMP8 (Glu2-Lys75).

靶标

Vesicle-associated membrane protein 8; VAMP-8; Endobrevin; EDB; VAMP8

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

Q9BV40, Q9WUF4, Q3T0Y8, O70404

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Vesicle-associated membrane protein 8 (VAMP8) is a ~11 kDa protein. SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. VAMP8 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane via its interaction with the STX17-SNAP29 binary t-SNARE complex. Also required for dense-granule secretion in platelets. Also plays a role in regulated enzyme secretion in pancreatic acinar cells.

1. Itakura, E. et al. (2012) Cell 151, 1256-69. PMID: 23217709

2. Diao, J. et al. (2015) Nature 520, 563-6. PMID: 25686604

3. Polgár, J. et al. (2002) Blood 100, 1081-3. PMID: 12130530

4. van Tol, S. et al. (2020) Journal of virology 94. PMID: 31694946

Note

For research use only

图片

参考文献

产品说明书

Anti-VAMP8 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-VAMP8 Polyclonal Antibody (HP094024)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-VAMP8 Polyclonal Antibody (HP094024)

概述

图片

参考文献

产品说明书

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