Anti-Human PLA2G5 Polyclonal Antibody (HA627014)

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概述
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参考文献
产品说明书

概述

货号

HA627014

品牌

abinScience

描述

Anti-Human PLA2G5 Polyclonal Antibody (HA627014) is a rabbit polyclonal antibody detecting Phospholipase A2 group V; 3.1.1.4; PLA2-10; Phosphatidylcholine 2-acylhydrolase 5; PLA2G5 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant human PLA2G5 (Gly21-Ser138).

靶标

Phospholipase A2 group V; 3.1.1.4; PLA2-10; Phosphatidylcholine 2-acylhydrolase 5; PLA2G5

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

P39877

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Phospholipase A2 group V (PLA2G5) is a ~15 kDa protein. Secretory calcium-dependent phospholipase A2 that primarily targets extracellular phospholipids. Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity), preferentially releasing fatty acyl groups with a low degree of unsaturation such as oleoyl (C18:1) and linoleoyl (C18:2) groups. Hydrolyzes low-density lipoprotein (LDL) phospholipids releasing unsaturated fatty acids that drive macrophage polarization toward an M2 phenotype. May act in an autocrine and paracrine manner. Contributes to lipid remodeling of cellular membranes at different subcellular locations and generation of lipid mediators involved in pathogen clearance.

1. Chen, J. et al. (1994) The Journal of biological chemistry 269, 2365-8. PMID: 8300559

2. Sun, YX. et al. (2004) The Biochemical journal 380, 749-56. PMID: 14998370

3. Hsu, YH. et al. (2013) PloS one 8, e59267. PMID: 23533611

4. Rubio, JM. et al. (2015) Journal of immunology (Baltimore, Md. : 1950) 194, 3327-39. PMID: 25725101

5. Koduri, RS. et al. (2002) The Journal of biological chemistry 277, 5849-57. PMID: 11694541

6. Kim, YJ. et al. (2002) The Journal of biological chemistry 277, 36479-88. PMID: 12124392

7. Muñoz, NM. et al. (2003) The Journal of biological chemistry 278, 38813-20. PMID: 12796497

Note

For research use only

图片

参考文献

产品说明书

Anti-Human PLA2G5 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human PLA2G5 Polyclonal Antibody (HA627014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human PLA2G5 Polyclonal Antibody (HA627014)

概述

图片

参考文献

产品说明书

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