Anti-EIF2S3 Polyclonal Antibody (HA632014)

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100ug

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概述
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概述

货号

HA632014

品牌

abinScience

描述

Anti-EIF2S3 Polyclonal Antibody (HA632014) is a rabbit polyclonal antibody detecting Eukaryotic translation initiation factor 2 subunit 3; 3.6.5.3; Eukaryotic translation initiation factor 2 subunit gamma X; eIF2-gamma X; eIF2gX; EIF2S3; EIF2G in ELISA, IHC, WB. Suitable for Human, Rat, Mouse, Pig, and Bovine.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant human EIF2S3 (Met1-Asp472).

靶标

Eukaryotic translation initiation factor 2 subunit 3; 3.6.5.3; Eukaryotic translation initiation factor 2 subunit gamma X; eIF2-gamma X; eIF2gX; EIF2S3; EIF2G

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

P41091, Q2VIR3, P81795, Q9Z0N1, P20461, Q2KHU8, Q5ZMS3, Q9Z0N2, C9WPN6, F1QGW6

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Eukaryotic translation initiation factor 2 subunit 3 (EIF2S3) is a ~51 kDa protein. Member of the eIF2 complex that functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form the 43S pre-initiation complex (43S PIC). Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF2 and release of an eIF2-GDP binary complex. In order for eIF2 to recycle and catalyze another round of initiation, the GDP bound to eIF2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.

1. Young-Baird, SK. et al. (2020) Molecular cell 77, 875-886.e7. PMID: 31836389

Note

For research use only

图片

参考文献

产品说明书

Anti-EIF2S3 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-EIF2S3 Polyclonal Antibody (HA632014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-EIF2S3 Polyclonal Antibody (HA632014)

概述

图片

参考文献

产品说明书

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