Anti-SLC1A4 Polyclonal Antibody (HA640014)

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概述
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参考文献
产品说明书

概述

货号

HA640014

品牌

abinScience

描述

Anti-SLC1A4 Polyclonal Antibody (HA640014) is a rabbit polyclonal antibody detecting Neutral amino acid transporter A; Alanine/serine/cysteine/threonine transporter 1; ASCT-1; Solute carrier family 1 member 4; SLC1A4; ASCT1; SATT in ELISA, IHC, WB. Suitable for Human and Bovine.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant human SLC1A4 (Lys140-Thr216).

靶标

Neutral amino acid transporter A; Alanine/serine/cysteine/threonine transporter 1; ASCT-1; Solute carrier family 1 member 4; SLC1A4; ASCT1; SATT

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

P43007, A2VDL4

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Neutral amino acid transporter A (SLC1A4) is a ~55 kDa protein. Sodium-coupled antiporter of neutral amino acids. In a tri-substrate transport cycle, exchanges neutral amino acids between the extracellular and intracellular compartments, coupled to the inward cotransport of at least one sodium ion. Exchanges neutral amino acids such as L- and D-serine, L-threonine, L-asparagine and L-alanine in a bidirectional way. Involved in homeostasis of D-serine, a coagonist of synaptic NMDA receptors. In astrocytes at excitatory synapses, mediates electrogenic D-serine influx coupled to L-serine efflux and L-serine shuttling to neurons for de novo D-serine synthesis.

1. Scopelliti, AJ. et al. (2014) The Journal of biological chemistry 289, 17468-79. PMID: 24808181

2. Foster, AC. et al. (2016) PloS one 11, e0156551. PMID: 27272177

3. Stehantsev, P. et al. (2021) Computational and structural biotechnology journal 19, 5246-5254. PMID: 34630942

4. Zerangue, N. et al. (1996) The Journal of biological chemistry 271, 27991-4. PMID: 8910405

5. Pinilla-Tenas, J. et al. (2003) The Journal of membrane biology 195, 27-32. PMID: 14502423

6. Damseh, N. et al. (2015) Journal of medical genetics 52, 541-7. PMID: 26041762

7. Arriza, JL. et al. (1993) The Journal of biological chemistry 268, 15329-32. PMID: 8101838

8. Shafqat, S. et al. (1993) The Journal of biological chemistry 268, 15351-5. PMID: 8340364

Note

For research use only

图片

参考文献

产品说明书

Anti-SLC1A4 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-SLC1A4 Polyclonal Antibody (HA640014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-SLC1A4 Polyclonal Antibody (HA640014)

概述

图片

参考文献

产品说明书

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