Anti-GUCA1A Polyclonal Antibody (HA643014)

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50ug
100ug

数量：

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概述
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参考文献
产品说明书

概述

货号

HA643014

品牌

abinScience

描述

Anti-GUCA1A Polyclonal Antibody (HA643014) is a rabbit polyclonal antibody detecting Guanylyl cyclase-activating protein 1; GCAP 1; Guanylate cyclase activator 1A; GUCA1A; C6orf131; GCAP; GCAP1; GUCA1 in ELISA, IHC, WB. Suitable for Human, Bovine, and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant human GUCA1A (Met1-Gly201).

靶标

Guanylyl cyclase-activating protein 1; GCAP 1; Guanylate cyclase activator 1A; GUCA1A; C6orf131; GCAP; GCAP1; GUCA1

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

P43080, P46065, P43081

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Guanylyl cyclase-activating protein 1 (GUCA1A) is a ~22 kDa protein. Stimulates retinal guanylyl cyclase when free calcium ions concentration is low and inhibits guanylyl cyclase when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of retinal guanylyl cyclase is a key event in recovery of the dark state of rod photoreceptors following light exposure. May be involved in cone photoreceptor light response and recovery of response in bright light.

1. Jiang, L. et al. (2008) Vision research 48, 2425-32. PMID: 18706439

2. Kitiratschky, VB. et al. (2009) Human mutation 30, E782-96. PMID: 19459154

3. Marino, V. et al. (2018) Human molecular genetics 27, 4204-4217. PMID: 30184081

4. Peshenko, IV. et al. (2019) The Journal of biological chemistry 294, 3476-3488. PMID: 30622141

Note

For research use only

图片

参考文献

产品说明书

Anti-GUCA1A Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-GUCA1A Polyclonal Antibody (HA643014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-GUCA1A Polyclonal Antibody (HA643014)

概述

图片

参考文献

产品说明书

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