Anti-Human CLCNKA Polyclonal Antibody (HA681014)

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50ug
100ug

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概述
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参考文献
产品说明书

概述

货号

HA681014

品牌

abinScience

描述

Anti-Human CLCNKA Polyclonal Antibody (HA681014) is a rabbit polyclonal antibody detecting Chloride channel protein ClC-Ka; Chloride channel Ka; ClC-K1; CLCNKA in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant human CLCNKA (Ala507-Lys687).

靶标

Chloride channel protein ClC-Ka; Chloride channel Ka; ClC-K1; CLCNKA

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

P51800, P51801

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Chloride channel protein ClC-Ka (CLCNKA) is a ~75 kDa protein. Anion-selective channel permeable to small monovalent anions with ion selectivity for chloride > bromide > nitrate > iodide. Forms a homodimeric channel where each subunit has its own ion conduction pathway. May conduct double-barreled currents controlled by two types of gates, two fast gates that control each subunit independently and a slow common gate that opens and shuts off both subunits simultaneously. Assembles with the regulatory subunit BSND/Barttin for sorting at the basolateral plasma membrane domain and functional switch to the ion conducting state. CLCNKA:BSND channels display mostly a linear current-voltage relationship with fast gating at negative potentials.

1. Estévez, R. et al. (2001) Nature 414, 558-61. PMID: 11734858

2. Waldegger, S. et al. (2002) Pflugers Archiv : European journal of physiology 444, 411-8. PMID: 12111250

3. Nozu, K. et al. (2008) Journal of medical genetics 45, 182-6. PMID: 18310267

4. Janssen, AG. et al. (2009) Journal of the American Society of Nephrology : JASN 20, 145-53. PMID: 18776122

5. Riazuddin, S. et al. (2009) American journal of human genetics 85, 273-80. PMID: 19646679

6. Fischer, M. et al. (2010) Journal of the American Society of Nephrology : JASN 21, 1281-9. PMID: 20538786

Note

For research use only

图片

参考文献

产品说明书

Anti-Human CLCNKA Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CLCNKA Polyclonal Antibody (HA681014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CLCNKA Polyclonal Antibody (HA681014)

概述

图片

参考文献

产品说明书

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