Anti-PTPN4 Polyclonal Antibody (HA691014)

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50ug
100ug

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概述
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参考文献
产品说明书

概述

货号

HA691014

品牌

abinScience

描述

Anti-PTPN4 Polyclonal Antibody (HA691014) is a rabbit polyclonal antibody detecting Tyrosine-protein phosphatase non-receptor type 4; 3.1.3.48; Protein-tyrosine phosphatase MEG1; MEG; PTPase-MEG1; PTPN4 in ELISA, IHC, WB. Suitable for Human and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human, Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant human PTPN4 (Asp636-Lys926).

靶标

Tyrosine-protein phosphatase non-receptor type 4; 3.1.3.48; Protein-tyrosine phosphatase MEG1; MEG; PTPase-MEG1; PTPN4

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

P29074, Q9WU22

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Tyrosine-protein phosphatase non-receptor type 4 (PTPN4) is a ~105 kDa protein. Phosphatase that plays a role in immunity, learning, synaptic plasticity or cell homeostasis. Regulates neuronal cell homeostasis by protecting neurons against apoptosis. Negatively regulates TLR4-induced interferon beta production by dephosphorylating adapter TICAM2 and inhibiting subsequent TRAM-TRIF interaction. Also dephosphorylates the immunoreceptor tyrosine-based activation motifs/ITAMs of the TCR zeta subunit and thereby negatively regulates TCR-mediated signaling pathway. May act at junctions between the membrane and the cytoskeleton.

1. Huai, W. et al. (2015) Journal of immunology (Baltimore, Md. : 1950) 194, 4458-65. PMID: 25825441

2. Maisonneuve, P. et al. (2016) The Journal of biological chemistry 291, 16699-708. PMID: 27246854

3. Préhaud, C. et al. (2010) Science signaling 3, ra5. PMID: 20086240

Note

For research use only

图片

参考文献

产品说明书

Anti-PTPN4 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-PTPN4 Polyclonal Antibody (HA691014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-PTPN4 Polyclonal Antibody (HA691014)

概述

图片

参考文献

产品说明书

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