Anti-IMPA1 Polyclonal Antibody (HA692014)

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50ug
100ug

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概述
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参考文献
产品说明书

概述

货号

HA692014

品牌

abinScience

描述

Anti-IMPA1 Polyclonal Antibody (HA692014) is a rabbit polyclonal antibody detecting Inositol monophosphatase 1; IMP 1; IMPase 1; 3.1.3.25; D-galactose 1-phosphate phosphatase; 3.1.3.94; Inositol-1(or 4)-monophosphatase 1; Lithium-sensitive myo-inositol monophosphatase A1; IMPA1; IMPA in ELISA, IHC, WB. Suitable for Human, Bovine, Mouse, and Pig.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant human IMPA1 (Met1-Asp277).

靶标

Inositol monophosphatase 1; IMP 1; IMPase 1; 3.1.3.25; D-galactose 1-phosphate phosphatase; 3.1.3.94; Inositol-1(or 4)-monophosphatase 1; Lithium-sensitive myo-inositol monophosphatase A1; IMPA1; IMPA

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

P29218, P20456, O55023, O77591

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Inositol monophosphatase 1 (IMPA1) is a ~30 kDa protein. Phosphatase involved in the dephosphorylation of myo-inositol monophosphates to generate myo-inositol. Is also able to dephosphorylate scyllo-inositol-phosphate, myo-inositol 1,4-diphosphate, scyllo-inositol-1,3-diphosphate and scyllo-inositol-1,4-diphosphate. Also dephosphorylates in vitro other sugar-phosphates including D-galactose-1-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate and 2'-AMP. Responsible for the provision of inositol required for synthesis of phosphatidylinositols and polyphosphoinositides, and involved in maintaining normal brain function. Has been implicated as the pharmacological target for lithium (Li(+)) action in brain, which is used to treat bipolar affective disorder.

1. Ohnishi, T. et al. (2007) The Journal of biological chemistry 282, 637-46. PMID: 17068342

2. Ganzhorn, AJ. et al. (1996) Biochemistry 35, 10957-66. PMID: 8718889

3. Parthasarathy, R. et al. (1997) Brain research 778, 99-106. PMID: 9462881

4. Figueiredo, T. et al. (2016) Molecular psychiatry 21, 1125-9. PMID: 26416544

Note

For research use only

图片

参考文献

产品说明书

Anti-IMPA1 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-IMPA1 Polyclonal Antibody (HA692014)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-IMPA1 Polyclonal Antibody (HA692014)

概述

图片

参考文献

产品说明书

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