Anti-PDLIM4 Polyclonal Antibody (HA712014)

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100ug

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概述
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参考文献
产品说明书

概述

货号

HA712014

品牌

abinScience

描述

Anti-PDLIM4 Polyclonal Antibody (HA712014) is a rabbit polyclonal antibody detecting PDZ and LIM domain protein 4; LIM protein RIL; Reversion-induced LIM protein; PDLIM4; RIL in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Bovine.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant human PDLIM4 (Pro2-Glu84).

靶标

PDZ and LIM domain protein 4; LIM protein RIL; Reversion-induced LIM protein; PDLIM4; RIL

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

P50479, P70271, P36202, Q3T005

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

PDZ and LIM domain protein 4 (PDLIM4) is a ~35 kDa protein. Suppresses SRC activation by recognizing and binding to active SRC and facilitating PTPN13-mediated dephosphorylation of SRC 'Tyr-419' leading to its inactivation. Inactivated SRC dissociates from this protein allowing the initiation of a new SRC inactivation cycle. Involved in reorganization of the actin cytoskeleton. In nonmuscle cells, binds to ACTN1 (alpha-actinin-1), increases the affinity of ACTN1 to F-actin (filamentous actin), and promotes formation of actin stress fibers. Involved in regulation of the synaptic AMPA receptor transport in dendritic spines of hippocampal pyramidal neurons directing the receptors toward an insertion at the postsynaptic membrane.

1. Zhang, Y. et al. (2009) The Journal of cell biology 184, 785-92. PMID: 19307596

2. Guryanova, OA. et al. (2011) The Journal of biological chemistry 286, 26849-59. PMID: 21636573

Note

For research use only

图片

Western blot

Lane 1: A431 cell lysate
Lane 2: K562 cell lysate
Lane 3: Mouse brain lysate
Lane 4: Rat brain lysate

参考文献

产品说明书

Anti-PDLIM4 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-PDLIM4 Polyclonal Antibody (HA712014)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-PDLIM4 Polyclonal Antibody (HA712014)

概述

图片

参考文献

产品说明书

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