

| 货号 | HA725014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-OTOF Polyclonal Antibody (HA725014) is a rabbit polyclonal antibody detecting Otoferlin; Fer-1-like protein 2; OTOF; FER1L2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Zebrafish.
Highlights
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| 种属反应性 | Human, Mouse, Rat | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant human OTOF (Met244-Ala596). | ||||||||
| 靶标 | Otoferlin; Fer-1-like protein 2; OTOF; FER1L2 | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q9HC10, Q9ESF1, Q9ERC5, Q5SPC5 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Otoferlin is a ~226 kDa protein. Key calcium ion sensor involved in the Ca(2+)-triggered synaptic vesicle-plasma membrane fusion and in the control of neurotransmitter release at these output synapses. Interacts in a calcium-dependent manner to the presynaptic SNARE proteins at ribbon synapses of cochlear inner hair cells (IHCs) to trigger exocytosis of neurotransmitter. Also essential to synaptic exocytosis in immature outer hair cells (OHCs). May also play a role within the recycling of endosomes. | ||||||||
| Note | For research use only |

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