

| 货号 | HA735014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 描述 |
Anti-LSM6 Polyclonal Antibody (HA735014) is a rabbit polyclonal antibody detecting U6 snRNA-associated Sm-like protein LSm6; LSM6 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
| ||||||||
| 种属反应性 | Human, Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant human LSM6 (Ser2-Met80). | ||||||||
| 靶标 | U6 snRNA-associated Sm-like protein LSm6; LSM6 | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P62312, P62313, Q9M1Z3 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
||||||||
| 产品使用信息 |
| ||||||||
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | U6 snRNA-associated Sm-like protein LSm6 is a ~9 kDa protein. Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway (Probable). 1. Bertram, K. et al. (2017) Cell 170, 701-713.e11. PMID: 28781166 2. Achsel, T. et al. (1999) The EMBO journal 18, 5789-802. PMID: 10523320 | ||||||||
| Note | For research use only |

24小时产品查询

扫一扫关注我们

专属渠道经理