

| 货号 | HA774014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human NKG7 Polyclonal Antibody (HA774014) is a rabbit polyclonal antibody detecting Protein NKG7; G-CSF-induced gene 1 protein; GIG-1 protein; Granule membrane protein of 17 kDa; GMP-17; Natural killer cell protein 7; p15-TIA-1; NKG7; GIG1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant human NKG7 (Phe29-Phe61). | ||||||||
| 靶标 | Protein NKG7; G-CSF-induced gene 1 protein; GIG-1 protein; Granule membrane protein of 17 kDa; GMP-17; Natural killer cell protein 7; p15-TIA-1; NKG7; GIG1 | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q16617 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Protein NKG7 is a ~17 kDa protein. Regulates cytotoxic granule exocytosis in effector lymphocytes, thus acting as a critical mediator of inflammation in a broad range of infectious and non-infectious diseases. Essential for cytotoxic degranulation of natural killer (NK) cells and CD8(+) T-cells and for the activation of CD4(+) T-cells following infection. Plays a critical role in CD8(+) T-cell and NK cell-mediated cytolysis of target cells and contributes to the cytolytic activity via the perforin/granzyme pathway by enhancing exocytosis of LAMP1-carrying lytic granules. Contributes to NK cell-mediated control of cancer metastasis. | ||||||||
| Note | For research use only |

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